Equid alphaherpesvirus type 8 (EHV-8) is a contagious pathogen that causes reproductive disorders, respiratory diseases, and viral encephalitis in equids, resulting in significant economic losses for the global horse and donkey industries.Currently, there are no approved antiviral drugs or vaccines available for EHV-8 control.In this study, we inve
IGFBP7 mediates oxLDL-induced human vascular endothelial cell injury by suppressing the expression of SIRT1
Endothelial cell injury plays an important role in initiating atherosclerotic lesion formation.Insulin-like growth factor binding protein 7 (IGFBP7) is known to modulate the behaviors of tumor-associated endothelial cells.This study was conducted to test whether IGFBP7 is involved in endothelial cell injury during atherosclerosis.Oxidized matcha po
Derogation of Human Rights in Emergency Situations; A Comparative Study of the Constitution of the Islamic Republic of Iran and the International Covenant on Civil and Political Rights
Human Rights treaties which contain derogation clause, albeit allowing the derogation of some rights and freedoms in states of emergency, have provided some principles that must be observed by the States Parties for the derogation clause to be applicable.The purpose behind the prevision is the prevention from abuse of derogation right and gross vio
Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia
Abstract Epithelia are tightly connected cellular sheets, that shield our body from the external environment.They are continuously maintained by a pooled population of undifferentiated cells through differentiation.However, the maintenance mechanisms remain Bib incompletely understood due to the difficulty of experimentally observing the differenti